Correspondence, notebooks, research data related to Cole's career as the first director at the Hospital of the Rockefeller Institute of Medical Research, 1908-1937. His research of pneumonia was conducted when the disease was epidemic. Personal correspondence reflect Cole's life as a medical resident at Johns Hopkins, 1899-1908. Documented are his memberships in leading medical organizations throughout his career, including the Association of American Physicians and the New York Academy of Medicine. This collection showcases the evolving changes in the medical profession from practicing physician to clinician.

An administrator and humanist, Henry Allen Moe (1894-1975) was the first director of the National Endowment for the Humanities, and was a president of the American Philosophical Society from 1959 to 1970. The Moe Papers are a vast and rich resource documenting all phases of Moe's career, but are also a major source of information on twentieth-century philanthropic organizations. As the first Secretary, then Administrator, and finally President of the John Simon Guggenheim Foundation (ca. 1925-1963), Moe made contact with the influential and the aspiring in the worlds of banking, finance, the arts, and sciences. This collection is particularly strong in correspondence and information relating to Latin America, much of it generated through Moe's oversight of the Guggenheim's Latin America Fund and by Moe's otherwise keen interest in the region. This material is diverse, ranging from material on agriculture (see Escuela Agricola Panamericana, 15 boxes) and Peruvian archaeology (see Alfred Kroeber's detailed report) to many folders of correspondence and grant reports from artists, writers, and politicians of South and Central America. Moe served as trustee, officer, and committee member of over thirty private foundations, many of which are well represented in the collection by yearly reports and grant applications, among other types of records.